There are no side effects from this all natural NAD+ IV Therapy. However, as you receive the IV therapy and it cleanses the receptors in your brain, it can cause nausea, heaviness of chest and limbs, stomach cramps, and headaches. Each patient varies in what they do or do not feel and is given special natural aids to assist in alleviated these discomforts. The items listed come in waves and are not continuous. These stop as soon as the NAD+ IV Therapy is stopped and they may be alleviated by slowing the drip rate of the iv. The benefits far outweigh the temporary discomfort.